Enrichment Sequencing

Introduction and Workflow

Enriched Sequencing is a comprehensive approach to analyze part of genomes base-by-base, providing enriched genomic view.
The workflow includes isolating DNA, fragmenting it, capturing the regions of interest followed by sequencing to produce millions of short reads.
In the bioinformatics analysis, these reads are aligned to a known reference genome to detect genomic alterations.
It is a powerful tool for diverse genomic studies, capable of sequencing humans, livestock, plants, bacteria, and disease-related microbes.

Provides a more affordable alternative to Whole Genome Sequencing (WGS), making it accessible to a wider range of researchers and clinicians.
Enhances detection of single-nucleotide variants (SNVs), copy number variants (CNVs), and insertions/deletions (InDels) with sensitivity and accuracy comparable to WGS, particularly in exonic regions.
Produces smaller data sets compared to WGS, allowing for quicker and more straightforward data analysis, which accelerates research and diagnostics.
Focuses on exonic regions, which are more likely to harbor disease-causing variants, leading to a more efficient and targeted approach in identifying genetic variants.

Genomic DNA, Cultivated cells, Blood, tissues, and other samples.

Please refer to sample submission guidelines or Contact Us!

Illumina NovaSeq 6000/ NovaSeq X