Introduction and Workflow
- Whole Genome Sequencing (WGS) is a comprehensive approach to analyze entire genomes base-by-base, providing a complete genomic view.
- The workflow includes isolating DNA, fragmenting it, and sequencing to produce millions of short reads.
- In the bioinformatics analysis, these reads are then assembled to construct the genome or aligned to a known reference genome.
- It is a powerful tool for diverse genomic studies, capable of sequencing humans, livestock, plants, bacteria, and disease-related microbes.
Advantages of Whole Genome Sequencing
- Provides a comprehensive, high-resolution view of the genome, surpassing the coverage offered by targeted sequencing.
- Identifies both small (SNVs, CNVs, InDels) and large structural variants that may be missed with targeted approaches, offering valuable insights into inherited genetic conditions and characterizing mutations driving cancer progression.
- Generates large volumes of data quickly, facilitating the assembly of novel genomes.
- Uncovers genomic diversity, taxonomic classifications, and evolutionary relationships, enhancing our understanding of biological complexity.
Service Specifications
Sample Requirement
Genomic DNA, Cultivated cells, Blood, tissues, and other samples.
Please refer to sample submission guidelines or Contact Us!
Sequencing Platform
Illumina NovaSeq 6000/ NovaSeq X
Deliverables
- The original sequencing data
- Experimental results
- Bioinformatics and Data Analysis Report
- Details in Whole Genome Denovo Sequencing (customizable)